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Restylane Refyne

A flexible filler for softer
folds and wrinkles

What is Restylane Refyne?

Restylane Refyne is one of many products in the Restylane family of hyaluronic acid-based dermal fillers with increased flexibility to treat dynamic facial lines and folds.

Restylane Refyne is an FDA-approved dermal filler for mild-moderate nasolabial folds and marionette lines. It’s fine-tuned for adding volume to soften dynamic laugh lines and/or expression lines.

How does Restylane Refyne differ
from other Restylane products?

Restylane and Restylane Refyne are both hyaluronic acid fillers in the Restylane product family.

Restylane Refyne contains cross-linked hyaluronic acid which makes it more durable and robust than original Restylane. The increased durability also means longer longevity. Compared to its close sister products, Restylane Defyne and Restylane Lyft,  Restylane Refyne is better formulated for correction of softer folds and wrinkles around the smile lines and mouth due to its finer particles. Although more flexible than other Restylane fillers, Refyne is still very durable. It is generally injected more superficially than its sister products.

How is Restylane Refyne commonly used?

With the age-related loss of skin hydration and elasticity, deep lines may form around the corners of the nose and mouth, and these nasolabial folds and/or marionette lines become much more visible.

Restylane Refyne’s 6% cross-linking hyaluronic acid composition makes it a great product to restore volume in facial areas with a lot of movement, such as the smile lines. Restylane Refyne is an extremely flexible filler product, and its soft support offers a very natural-looking solution to finer wrinkles of the nasolabial areas of the face.

How long do results last?

Restylane Refyne is more durable than Restylane and it generally lasts up to around 12 months before retreatment may be needed!

Are there side effects to be aware
of with Restylane Refyne?

According to the Restylane website, the most commonly observed side effects are swelling, redness, pain, and bruising at the injection site. These are typically quite mild, and they should dissipate within several days depending on the treatment site.  Dr. Brandish uses a soft-tipped cannula to inject dermal fillers which makes the procedure much safer to administer.

More information about side effects can be found on Restylane USA’s website.

Restylane Refyne Summary

Restylane Refyne is a cross-linked hyaluronic acid-based filler with a strong but extremely flexible formula. It’s a great tool for restoring natural-looking volume in areas of more mild, superficial facial wrinkles (like laugh lines around the mouth and nose). Its improved formula provides a great balance between durability, volume, and versatility.

How do I get started?

If you’re interested in hearing more or in scheduling an appointment, contact our office at

and we’ll take care of you. We offer free consultation appointments as well if you’d like to simply go over any problem areas and see if Restylane or other treatment options may be the most effective solution.